Autophagy has been linked to longevity in many species, but the underlying mechanisms are unclear.Using a GFP-tagged and a new tandem-tagged Atg8/LGG-1 reporter, we quantified DNA autophagic vesicles and performed autophagic flux assays in multiple tissues of wild-type Caenorhabditis elegans and long-lived daf-2/insulin/IGF-1 and glp-1/Notch mutant

Diabetic wounds are the most critical complication in patients with diabetes, which often lead to hospitalization and limb amputations.Diabetic foot ulcers (DFU) is characterized by infections, prolonged inflammation, and a Diffusers delayed wound healing process.Different types of medical procedures including surgical therapy, drug delivery, stem

Grid-connected inverters have a very significant role in the integration of renewable energy resources with utility grids.However, in recent studies, it is revealed that grid-connected inverters are vulnerable to instability when the nature of the grid changes from strong to weak, which produces uncertainty and performance degradation.An increase i

Here we report the monitoring of the digestive tract colonization of Rhodnius prolixus by Trypanosoma cruzi using an accurate determination of the parasite load by qPCR coupled with fluorescence and bioluminescence imaging (BLI).These complementary methods revealed critical steps necessary for the parasite population to colonize the insect gut and

Adult muscle stem cells, satellite cells (SCs), endow skeletal muscle with tremendous regenerative capacity.Upon injury, SCs activate, proliferate, and migrate DNA as myoblasts to the injury site where they become myocytes that fuse to form new muscle.How migration is regulated, though, remains largely unknown.Additionally, how migration and fusion